منابع مشابه
CD5- mantle cell lymphoma.
Mantle cell lymphoma (MCL) typically expresses B-cell antigens and CD5 and overexpresses bcl-1 protein. However, unusual cases of bcl-1+ and CD5-MCL have been observed, posing a practical challenge for correct diagnosis and management. We identified 25 cases (48 samples) of bcl-1+ and CD5- lymphoma. CD5 expression was assessed by flow cytometric analysis alone (1 case), immunohistochemical anal...
متن کاملPolymorphism in the CD5 gene promoter in B-cell chronic lymphocytic leukemia and mantle cell lymphoma.
Despite the low incidence of microsatellite instability (MSI) in lymphoid malignant neoplasms, it has been reported that the CD5 promoter MSI was relatively frequent among B-cell chronic lymphoproliferative disorders. We studied the presence of MSI in the CD5 promoter in 134 cases of B-cell chronic lymphocytic leukemia (B-CLL) and 47 of mantle cell lymphoma (MCL) by comparing the pattern of mic...
متن کاملMantle Cell Lymphoma with Multiple Lymphomatous Polyposis Presenting With Intussusceptions
Mantle cell lymphoma is an aggressive type of B-cell non-Hodgkin's lymphoma that originates from small to medium sized lymphocytes located in the mantle zone of the lymph node. The gastrointestinal tract is the predominant site of extranodal involvement in the form of multiple lymphomatous polyposis. Multiple lymphomatous polyposis due to mantle cell lymphoma presenting with intussusception is ...
متن کاملCD5-negative Blastoid Variant Mantle Cell Lymphoma with Complex CCND1/IGH and MYC Aberrations
The coexistence of CCND1/IGH and MYC rearrangements in mantle cell lymphoma (MCL) is a rare finding associated with a very poor prognosis. In this study, a patient with blastoid variant (MCL) is reported. The disease was clinically aggressive and refractory to chemotherapy, and the patient only survived for 1 month following diagnosis. Conventional cytogenetic study, FISH, and multicolor FISH (...
متن کاملHematopathology / LEUKEMIC MANTLE CELL LYMPHOMA WITH A CD5–, CD10+ BLASTOID COMPONENT
Materials and Methods Flow cytometric immunophenotyping analysis was performed according to previously described methods.11 Hematopathology / CASE REPORT Am J Clin Pathol 2004;122:122-127 123 123 DOI: 10.1309/UD2C6JVPWHXQQ217 123 © American Society for Clinical Pathology Following isotonic lysis, nucleated cells were stained with fluorochrome-conjugated antibodies to the following antigens: CD3...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2002
ISSN: 0002-9173,1943-7722
DOI: 10.1309/te56-a43x-29tt-5h8g